Tag Archives: Post-Doc

Postdoctoral Position at the Weizmann Institute

A Postdoctoral position to study Ferroptosis in cancer 

A three-years Postdoctoral position is available at the Weizmann Institute of Science to study the role of ferroptosis in breast cancer development and treatment

We employ multidisciplinary experimental approaches including advanced molecular cell biology methods, High Throughput drugs Screens, cell signaling and bioinformatics tools utilizing in vitro cellular models and in vivo animal models as well as cancer patient samples. 

We search for a highly motivated candidate with a background in cell signaling and  biochemistry. Individuals with experience with animal models are preferred

Applications with a CV and up to three contacts for references should be sent to:

Prof. Sima Lev

Department of Molecular Cell Biology, 

The Weizmann Institute of Science,

Rehovot 76100, Israel. 

Email:  sima.lev@weizmann.ac.il

Tel: 972-8-934-2126

http://www.weizmann.ac.il/mcb/Lev/

Post-doctoral Fellow – University of Oxford

A two-year post-doctoral research fellow position is available in the Drakesmith lab at the Weatherall Institute of Molecular Medicine, University of Oxford.

https://www.rdm.ox.ac.uk/people/alexander-drakesmith

With the support of an unrestricted grant from the pharmaceutical industry, the University of Oxford has driven the development of HIRO (Human Iron Research in Oxford), a cross-divisional initiative serving to link clinicians and scientists with an interest in iron research across the Oxford campuses; HIRO is led by Dr John Ryan and Prof Hal Drakesmith. Reporting to the Principal Investigator and the HIRO steering committee, the post holder will be the HIRO Fellow, a member of a research group with responsibility for carrying out studies on human-focussed translational iron research for patient benefit. The Drakesmith group is sited within the MRC Human Immunology Unit at the Weatherall Institute of Molecular Medicine. We have a strong track record in the field of iron metabolism with a specific interest in how iron trafficking interacts with infection, inflammation, immunology and anaemia. This specific project will build on published and unpublished ongoing studies relating to how iron availability controls inflammation and immunity and will involve interaction with academic groups within and beyond Oxford. The post holder provides guidance to junior members of the research group including research assistants, PhD students, and/or project volunteers. The post-holder will also work to connect the other HIRO-funded projects within the University of Oxford.

Please find further details of the position and how to apply here.

 

Postdoctoral Research Fellow in Iron Biology – IRSD Toulouse, France

A postdoctoral research fellow position is available for 3 years in the Delphine Meynard research group (http://en.irsd.fr/team-4-genetics-and-regulation-of-iron-metabolism.html).  We are part of the Digestive Health Research Institute (IRSD) in Toulouse in France. Toulouse is a dynamic research area located in south of France that comprises many internationally recognized laboratories and gives access to a network of high-level skills research platforms in life sciences (fundamental biology, agronomy, environment, health) making possible almost all research projects.

The Digestive Health Research Institute accredited by INSERM, INRA, ENVT and Toulouse University, is internationally recognized and offerins a productive scientific environment centered on basic and clinical research to understand and treat diseases of the intestine and the liver. IRSD brings together a total of >80 researchers, professors, technicians, students and post-docs of different nationalities.

Our research focuses on iron metabolism and its disturbance in human diseases. Our lab is a dynamic team of scientists, MD, graduate students, and technicians. Our main goal is to characterize the regulation of iron homeostasis at the cellular and molecular levels and to develop new therapeutic strategies for the treatment of iron related disorders. The postdoctoral project will specifically address the role of proteases in the regulation of iron homeostasis and develop new strategies to target those proteases. The postdoctoral fellow will use several approaches including molecular and cellular biology, animal models, and biochemistry but also techniques related to proteases such as enzymatic activity assay, activity based probes, and in situ zymography.

Applicants for this position must have a Ph.D. in the biochemical sciences. A suitable candidate will have a proven track record of research accomplishments including first author publications in international peer-reviewed journals and excellent experience in: molecular and cellular biology, biochemistry, mouse models. Skills with proteases would be appreciable. In addition, excellent communication/interpersonal skills are required.

Please email a cover letter, CV, and two letters of support from former mentors or collaborators (including their contact information) to Delphine Meynard: delphine.meynard@inserm.fr

Postdoctoral Research Fellow in Iron Biology, New York Blood Center (NYBC, New York, NY)

A postdoctoral research fellow position is available in the Vinchi Laboratory at the New York Blood Center. We are currently seeking PostDoc candidates to investigate mechanisms of heme/iron-driven inflammation and oxidative stress within the Iron Research Program of the institute. We are part of the Lindsley F. Kimball Research Institute, the research branch of the New York Blood Center, one of the most comprehensive blood centers in the world. NYBC focus is on cultivating excellence by merging cutting-edge innovation with diligent customer service, groundbreaking research, and comprehensive program and service development. The main goal of the Iron Program is to investigate the impact of iron overload and deficiency on the pathogenesis of human diseases, including sickle cell disease, cardiovascular disease and cancer. Our research investigates the molecular mechanisms of heme/iron-driven inflammation, oxidative stress and vascular dysfunction, and the role of detoxification systems in counteracting these effects. The candidate will perform cutting-edge research that integrates human biology and hematology with novel therapies using innovative technologies and approaches including classic molecular, cellular, and biochemical techniques, as well as modern imaging, sequencing and single cell analysis techniques, bioinformatics, and preclinical in vitro and in vivo models.  In addition, he/she will collaborate with other research scientists across the NYBC, including basic and translational investigators.

Requirements include:

  • D. and/or M.D. degree in the biomedical sciences
  • A good record of high impact publications and a strong scholarly record
  • An experimental background in molecular and cellular biology (research experience with mouse models is required)
  • Ability to work independently and within a strong team environment; to identify problems in a timely manner, evaluate options and implement solutions; trong attention to detail in all work processes
  • Participation in team meetings and contribution to experimental design

 

For immediate consideration, please submit an application to Dr. Francesca Vinchi, Head of Iron Research Program (FVinchi@nybc.org),  including:

  • a full CV, including a list of publications
  • a motivational letter concisely describing your past research experience, your research interests and why you are applying
  • two letters of recommendation by referees (including their contact information)

 

To learn more about the Iron Research Program and the NYBC visit:

https://nybloodcenter.org/lindsley-f-kimball-research-institute/investigators/francesca-vinchi-phd/

www.nybloodcenter.org

 

Post – BioIron Forum November 2018 (Word)

Post-Doctoral Research Associate

BioIron Job Posting Kosman (PDF)

The kosmanlab
Dan Kosman
SUNY Distinguished Professor, Biochemistry

Funded by NINDDS to 2022

The objective of this Research Associate’s research is to examine the mechanisms by which eukaryotic cells take up and effllux the essential trace metals, iron and manganese. A specific focus is on the role of the amyloid precursor protein in modulating iron trafficking across the blood-brain barrier. These studies are carried out primarily in cultured mammalian cells, and primary cultures of capillary endothelial cells, astrocytes and neurons removed from mice and rats. In addition, the structure and function aspects of recombinant forms of proteins involved in these iron trafficking processes will be examined by biophysical (isothermal calorimetry, circular dichroism) and cell biologic approaches. This research involves a variety of methods including extensive use of molecular biologic/protein engineering techniques (recombinant DNA technology); cell culture; protein localization (indirect immunofluorescence, FRET); protein expression and purification; enzyme and various analyte assays (ELISAs); protein biophysical quantification (enzyme kinetics, isothermal calorimetry, circular dichroism); cellular metabolite (59Fe- and 54Mn-trafficking) kinetics.

The kosmanlab is located in the brand-new Jacobs School of Medicine and Biomedical Sciences of the University at Buffalo. Take a look at our new digs at http://kosmanlab.com/

We want to recruit a new Ph.D. to our group, one who has a demonstrated ability to work independently and to supervise less-experienced trainees. The successful candidate will be eligible for and qualified as a recipient of extramural fellowship support. Seeking such funds is a critical aspect of post-doctoral training.

To apply go to https://www.ubjobs.buffalo.edu/postings/14267

After you complete your application, please
contact Dr. Kosman directly at camkos@buffalo.edu

We look forward to hearing from you!